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Chunk #8 — Material and methods — Data recordings and preprocessing

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Subthalamic nucleus phase-amplitude coupling correlates with motor impairment in Parkinson's disease.
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and to focus their attention on a fixation cross without performing any explicit task. Separate experimental sessions were performed, for 13 out of 19 subjects on subsequent days, whilst the patient was either “ON” or “OFF” their normal dose of dopaminergic medication (after overnight withdrawal for the OFF state). The order of these sessions was counterbalanced across subjects. For a minority of subjects we were only able to obtain ON state recordings (5 cases) or OFF state recordings (9 cases). In 17 out of 53 recording sessions subjects performed the 3-min resting block twice, for the other sessions we had one block available.