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Chunk #12 — Results — Cell-type enrichment of expression of potential depression-causal genes

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Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
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In addition, among the 25 potentially causal genes from the depression PWAS meta-analysis, 13 were enriched in one or more cell types – five in excitatory neurons, five in inhibitory neurons, six in astrocytes, two in microglia, and one in oligodendrocytes (Figure 3b; Supplementary Table 16b).