The second study group consists of participants of the National FINRISK 2007 Study, which was carried out in Finland in 2007. The study was approved by the Coordinating Ethics Committee of the Hospital District of Helsinki and Uusimaa (229/EO/2006). Also the FINRISK was a nationwide health examination study based on the general adult population (Aalto et al., 2009). The sample was randomly selected from the Population Register Centre and was stratified according to sex, 10-year age groups and five geographical areas.