carried by each individual (based on the genotypes of family members) and assigned each individual a score ranging between 0 and 2 (47). This estimate incorporates allele frequency information, the genotypes of relatives for the SNP of interest, and flanking marker data. For computational efficiency, the Lander-Green algorithm was applied to sub-pedigrees, each including no more than 20-25 individuals, resulting in a dataset where the average analysis unit consisted of a family with 12.3 members and 3.2 generations.
