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Chunk #6 — INTRODUCTION

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Nicotine withdrawal sensitivity, linkage to chr6q26, and association of OPRM1 SNPs in the SMOking in FAMilies (SMOFAM) sample.
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Herein we present findings regarding an association between the Rasch modeled nicotine withdrawal sensitivity score and smoking relapse. We also present the results of an autosome-wide linkage analysis, and a family based association analysis at the OPRM1 gene to the Rasch modeled nicotine withdrawal sensitivity score using microsatellite genotypes and OPRM1 SNPs available in the SMOFAM dataset.