In this paper, we present new data on the ALDH2*504Lys frequency of 4,091 individuals in 86 populations from China, Laos, Vietnam, Russia, Japan, and other countries around the world (Table 1). Various collaborating laboratories have used different typing methods of either traditional PCR-RFLP (Oota et al., 2004) or Taqman® SNP genotyping assay (C__11703892_10). Added to the data we have extracted from the literature, the total sample size is 80,691 individuals from 366 population samples (see Table S1 and ALFRED online database for detailed data including references to the relevant geographic areas and ethnic groups).
