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Chunk #18 — Discussion

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Age of first drinking and adult alcohol problems: systematic review of prospective cohort studies.
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The most important study finding is the meagre evidence base available, with only a small number of heterogeneous studies providing an insecure basis for making conclusions on the relationship between AFD and adult alcohol problems. There is some evidence of at least small, rather inconsistent, effects of AFD on adult alcohol problems in all studies, however these effects attenuate or disappear with more rigorous control for confounding. The included studies are not without limitations which are important to consider before drawing conclusions.