VS receives the most limited input, primarily derived from the VTA. The rest of the VS receives input from the entire dorsal tier and from the most medial and dorsal part of the ventral tier. In contrast to the VS, the central striatal area (the region innervated by the dPFC) receives input from a wide region of the ventral tier. In addition to an inverse topography, there is also a differential ratio of DA projections to the different striatal areas. The input to the VS is derived from the most limited midbrain region, whereas the input to the dorsolateral striatum is derived from the largest midbrain area.13
