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Chunk #41 — Discussion — Limitations

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Regional growth trajectories of cortical myelination in adolescents and young adults: longitudinal validation and functional correlates.
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More complex modelling would also be required when further testing relations between the development of myelin content and neuropsychological functioning. The current analysis focused on correlating normalized myelin content to the Grooved Pegboard Test scores of the NCANDA cohort. Measurements capturing more complex neuropsychological functioning, such as derived from resting-state fMRI, have been collected by the HCP and NCANDA study but harmonizing those across studies is generally challenging. When done accurately, one could gain a refined view of the development of cortical myelin and function throughout the brain.