The pair-wise option of Tagger32 (implemented in Haploview)33 with a threshold of r2≥0.8 for most genes and r2≥0.9 for high-priority candidates (e.g., opioid receptor genes) was used to select a custom set of 1536 SNPs. The set provided coverage of 72 candidate genes, 47 additional SNPs from prior reports, and 30 ancestry-informative markers (AIMs).