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Chunk #8 — Method — Participants

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Most of the genetic covariation between major depressive and alcohol use disorders is explained by trait measures of negative emotionality and behavioral control.
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Participants were 3623 members of the Australian Twin Registry (ATR) Cohort II. In 1980–1982, a sample of 4268 twin pairs born during 1964–1971 were registered with the ATR, in response to appeals though the media and Australian school systems. They were first surveyed in 1989–1992. Data in the current study were collected in 2004–2007, for a study primarily focused on gambling (Slutske et al. 2009), via structured diagnostic telephone interview and mailed self-report questionnaire [interview: n = 4764 twins, mean age = 37.7 years (range = 32–43), response rate = 80%; questionnaire: n = 4369 twins, response rate = 92%]. The current study was based on data from same-sex monozygotic (MZ) and dizygotic (DZ) twins. There were 1461 complete twin pairs [867 MZ (347 male, 520 female), 594 DZ (227 male, 367 female)] and 701 twins from incomplete pairs [304 MZ (153 male, 151 female), 397 DZ (216 male, 181 female)].