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Chunk #10 — METHODS AND MATERIALS — CNV Predictions

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Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism.
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Genotypic data from all samples, including both cases and controls, were processed by three CNV detection algorithms: PennCNV (Rev. 220) (53), QuantiSNP (v1.1) (54), and GNOSIS (38). The results of all three algorithms were analyzed and merged using the program CNVision ((38) and http://www.cnvision.org) (Figure 1) (see Methods in Supplement 1).