Genotypic data from all samples, including both cases and controls, were processed by three CNV detection algorithms: PennCNV (Rev. 220) (53), QuantiSNP (v1.1) (54), and GNOSIS (38). The results of all three algorithms were analyzed and merged using the program CNVision ((38) and http://www.cnvision.org) (Figure 1) (see Methods in Supplement 1).