al. 2011). Genetic variants in the following genes APOE, DISC1, GAD1, GPCD1, ESR1, DYX1C1, DCD2, KIAA0319, HOXA1, DTNBP1, OXTR, MAOA, IL-6, MET and PER2, have been associated with neuroimaging phenotypes, raising the possibility that they may be involved in brain development (Shaw et al. 2007; Reiman et al. 2009; Furman et al. 2011; Tognin et al. 2011; Darki et al. 2012; Hedrick et al. 2012; Raznahan et al. 2012; Forbes et al. 2012; Ziermans et al. 2012; Knickmeyer et al. 2013). However, these studies need replication in independent cohorts, in part to evaluate for possible racial and ethnic differences, since the study populations were primarily Caucasian. Moreover, potential interactions between genetic variants, sex, and age need to be investigated further.
