including IL-6, IL-1, and TNF-α. In addition to affecting the innate immune system through inflammatory changes, alterations in CD14 function by alcohol exposure are also associated with the neuroinflammation and brain damage associated with alcohol misuse [10]. Multiple studies have shown that Cd14’s function is altered by ethanol consumption. However, the mechanisms through which Cd14 regulates ethanol response and interacts with other genes are still unclear.
