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Chunk #2 — METHODS — SNP SELECTION FOR REPLICATION STUDIES

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A comprehensive family-based replication study of schizophrenia genes.
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across 6 different microarray platforms using postmortem brain tissue from SCZ cases and controls14; the OMIM database of disease genes; human orthologs of mouse genes associated with behavioral phenotypes relevant to neuropsychiatric outcomes15; and SNPs strongly associated with variation in transcript abundance in the cortex (http://eqtl.uchicago.edu). A total of 8107 of the 9380 selected SNPs were successfully genotyped with the Illumina iSelect assay (http://www.illumina.com/products/infinium_iselect_custom_genotyping_beadchips.ilmn), with a call rate of 99.94%.