Chunk #9 — Methods — Coloc Analysis

Source

Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets.

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We used the default Coloc priors of p1 = 10−4, p2 = 10−4, and p12 = 10−5, where p1 is the probability that a given SNV is associated with PD, p2 is the probability that a given SNV is a significant eQTL, and p12 is the probability that a given SNV is both a PD result and an eQTL.