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Chunk #46 — METHODS — Identifying and classifying clonal mosaic anomalies

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Detectable clonal mosaicism from birth to old age and its relationship to cancer.
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All anomalies discussed in this paper are autosomal in the reference genome. Detection of X chromosome mosaics is complicated by the fact that LRR is a measure of the intensity of a sample relative to other samples. X chromosome LRR values (calculated in the standard way) are affected by the sex ratio in the sample set and are not comparable to those for the autosomes.