Chunk #48 — Materials and Methods — Human genetic association study — Genotyping

Source

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.

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Genotyping was performed blind to personality data, and the call rate was 99%. The distribution of our observed genotypes (CC = 539, AC = 295 and AA = 48) did not deviate from Hardy–Weinberg equilibrium (χ2 = 1.14, P = 0.56). To minimize the risk of artifacts due to population stratification, we restricted analyses to Caucasian participants, after which both genotyping and personality data were available for 881 individuals.