Liver sections were stained with H&E for pathological evaluation. Steatosis was quantified as the percentage of cells containing fatty droplets. Necroinflammation was quantified as the number of clusters of 5 or more inflammatory cells per square millimeter. Five 200× fields per liver were examined (one 200× field area = 0.95 mm2). Histopathology was performed on a fee for service basis by the Mount Sinai Pathology Core. The pathologist (S.C.W) was unaware of the treatment groups when evaluating the slides.
