All subjects were participants in the published Mayo LOAD GWAS [29] as part of the autopsy-based series (AUT_60–80). All subjects had neuropathologic evaluation by DWD. All ADs had definite diagnosis according to the NINCDS-ADRDA criteria [55] and had Braak scores of ≥4.0. All non–ADs had Braak scores of ≤2.5, and many had brain pathology unrelated to AD (Supplementary Tables 1 and 2 in Dataset S1). Three-hundred forty subjects had measurements in both cerebellum and temporal cortex. This study was approved by the appropriate institutional review board.
