paperKB
coga / coga-kb
Processing
Help
Sign in

Chunk #7 — Introduction

Source
Initial evidence that OPRM1 genotype moderates ventral and dorsal striatum functional connectivity during alcohol cues.
Embedded
yes

Text

connectivity in G-allele carriers. Alternatively, stronger connectivity in G-allele carriers would suggest a greater need for frontal regulation of disproportionately greater reward sensitivity in this group. No differences in dorsal striatal connectivity were hypothesized, as this polymorphism has not been implicated in habitual drinking. Given the hypothesized contribution of alcoholism severity to the shift from ventral to dorsal striatum control of alcohol cues processing (Vollstadt-Klein et al., 2010), analyses control for alcoholism severity.