Since its inception, the PANTHER website has provided, for a limited set of ‘fully supported’ genomes (human, mouse, rat and fruit fly), the following functionality: (i) stored classifications for all protein-coding genes, including family, subfamily, molecular function, biological process and pathway, (ii) visualization tools such as the whole genome pie chart view (Figure 3) of gene functions and (iii) analysis tools such as the Gene Expression Analysis Tool (10) for analyzing user-generated data relative to PANTHER classifications. For version 7, we have increased the number of fully supported genomes from 4 to 12 organisms, those participating in the GO Reference Genome Project (5), listed at the beginning of Table 1.
