Impulsivity is proposed to relate to increased substance use by an increased proclivity to act on the immediate reward associated with substance use without consideration of the long-term consequences of substance use [46]. NU may be related to increased drug use because of susceptibility to impulsive action in response to the stress of drug withdrawal and craving [21]. However, the results in the present study do not support a significant association between NU and functional connectivity of the LECN. It is possible that our sample size was too small to detect a subtle association between LECN functional connectivity and NU. Future work should further investigate whether LECN functional connectivity is associated with impulsivity and executive control task performance in larger samples of HC and OUD subjects.
