Since the initial release in 2003, PANTHER has become one of the most popular online resources for genome wide data analysis. Currently, there are over 7000 registered users, 600–800 daily users (weekdays) and over 14,000 monthly users worldwide. These counts were based on unique Internet Protocol (IP) addresses accessing the site, so the actual number is even greater. PANTHER has been cited in over 3600 publications since 2003 based on Google Scholar, and is growing steadily. Users have successfully analyzed the data from gene expression 9,10, proteomics 11,12 and genome-wide association study (GWAS) experiments13,14 in a diverse area of research, such as cancer research 10,11, neurological disorder studies 15,16, autoimmune diseases 9 and cardiac disease studies14,17.
