We separate the simulation results into nine groups that are combinations of three disease models and three K values (0.01, 0.1 and 0.2). In each group there are 100∼120 settings with different R and f values. With each setting we generate 1,000 trios and replicate the inference and dTDT procedures. Because of the large number of these settings (1,320 in total), we attach the results as in supplement tables. A plot of the for these models is shown in Figure 5 . In the figure, graphs from the top row to the bottom row represent the dominant, recessive and codominant models respectively, and from left to right represent the results with three different K values (0.01, 0.1 and 0.2). Each blue dot corresponds to a/under that specific setting.
