FASTSNP is available at . Users can choose from three different methods to specify their SNPs as the input to query FASTSNP. The main query method is ‘Query by Candidate Gene.’ The user can choose to specify a gene symbol, SNP reference cluster ID (rsid), or a chromosome position as the query. Since the functional effects of an SNP may be different in different transcripts of the gene, FASTSNP will provide the transcripts of the queried gene for users to select before it outputs the set of SNPs on the queried gene. The user further refines the set of SNPs by specifying the region whether the SNPs are coding or non-coding and the allele frequency. After a final set of candidate SNPs is selected, FASTSNP will perform the SNP prioritization described earlier, return the prioritization results in a risk ranking report, and provide a function report for each candidate SNP. FASTSNP also provides ‘Query by SNP’ which allows the user to specify a single SNP rs ID or upload an Excel file containing their entire candidate SNPs for prioritization. Finally,
