TLI and CUD (z = 6.28, p < .001). Confirmation of common liability was further obtained by the finding that probability of alcohol use predicts CUD (OR = 2.75, p < .001, 95% CI [1.89, 4.01]) and probability of cannabis use predicts AUD (OR = 3.29, p < .001, 95% CI [2.23, 4.85]). Indeed, even after taking into account differences in probability of consumption, alcohol use mediates the association between TLI and CUD (z = 6.65, p < .001) and cannabis use mediates the association between TLI and AUD (z = 6.46, p < .001).
