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Chunk #33 — Genome-wide association studies of alcohol dependence

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Genetic studies of alcohol dependence in the context of the addiction cycle.
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complex traits and disease, especially for psychiatric disorders. In addition, very stringent statistical corrections are required to control for multiple testing leading to an increase in false-positives due to >1 million SNPs typically interrogated in a single GWAS. A Bonferroni-corrected genome-wide significance threshold set at p < 10–8 is required.