While our sample sizes were smaller in the other race/ethnicity groups than for the non-Hispanic whites, we noticed that Latinos had the highest standardized GRS, followed closely by non-Hispanic whites, and then by East Asians and African Americans. In African Americans, European ancestry was associated with lower BP, but individuals with more European ancestry had higher BP standardized GRS (created from previously-described SNPs); this is counter-intuitive, but may reflect the fact that the GWAS discovery occurred primarily in European ancestry individuals, and suggests there may be other SNPs in African Americans remaining to be identified.
