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Chunk #10 — Materials and methods — RNA-seq analysis of miRNA and mRNA transcriptomic changes in eight brain regions of AUD subjects (192 Set 1 RNA samples)

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Exploration of alcohol use disorder-associated brain miRNA-mRNA regulatory networks.
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Aligner) was 73.2%. Principal component analysis (PCA) of miRNA transcriptome data of these 192 samples (from 8 brain regions) showed clustered CRB and VTA samples, but samples from six other brain regions could not be separated by brain regions using the miRNA expression data (Fig. S1a). The small RNA-seq fastq files and normalized read counts are available for downloading from the NCBI Gene Expression Omnibus (GEO) database (accession number: GSE181520).