For the continuous trait alcohol use outcome, estimates indicate the change in SDs per one SD change in either intercept or slope of depressive symptoms. For males, results show little evidence of a relationship between baseline levels or change in depressive symptoms and later alcohol use. In females, there is weak evidence (p ~ 0.02) of an association for change in depression symptoms, however this effect is small in magnitude. Adjustment for potential confounders has little effect on these estimates.