During the first 10 weeks of sarcosine administration at 2 g per day, the patient reported a gradual improvement of overall activity, concentration, and mood. After the next 2 weeks, the patient reported moderately increased mood, drive, and libido, excessive activity with talkativity, and decreased need for sleep (to 2–4 hours). The patient found these symptoms “strange” and asked for the modification of the treatment. She described the overall impact of sarcosine as positive, and therefore it was decided to maintain the sarcosine supplementation, but the dose of venlafaxine was been reduced by half to 37.5 mg per day. The patient declared adherence to the medication regimen.
