Chunk #10 — Results — ZBTB16 promotes inflammasome activity

Source

Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC.

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yes

Text

Together these data identify that ZBTB16 affects inflammasome activity without any conspicuous effect on the levels of the signalling components. Accordingly, ZBTB16 does not appear to be controlling inflammasome activity by its recognised function as a transcription factor.