The MOAFTS study was approved by the Washington University Human Research Protections Office. Data were collected by trained interviewers through a psychiatric interview modified for telephone administration from the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) (Bucholz et al., 1994, Hesselbrock et al., 1999). The SSAGA queries history of substance use and related psychosocial history in addition to diagnostic information for DSM-IV psychiatric disorders. Waves 1, 3, and 4 interviews assessed lifetime psychiatric and psychosocial history. Wave 5 interviews, which were conducted approximately 2 years after Wave 4 interviews, queried the previous 2 years (i.e., roughly the period between Wave 4 and Wave 5 assessments). Verbal consent was obtained prior to starting interviews.
