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Chunk #26 — Discussion

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Resting state fMRI connectivity is sensitive to laminar connectional architecture in the human brain.
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this study. In addition, optical imaging technique used by Chen et al. was invasive, and hence is not suitable for human studies. In this study, we approached this issue in terms of HRF differences across layers. We reasoned that any differences between BOLD signals across layers that have a vascular origin, must be reduced or eliminated if voxel (or vertex-specific) HRF was deconvolved from the BOLD data and connectivity estimation was performed in the latent neural space.