shows users the number of drugs and associated drug targets within each drug category. Similarly, ‘Pathways’ can be searched by the pathway name, the pathway category (such as ‘Metabolic’, ‘Physiological’, ‘Signaling’, ‘Drug metabolism’, ‘Drug action’ or ‘Disease’), or by any of the drugs associated with that pathway. ‘Drug Reactions’ refers primarily to drug metabolic reactions corresponding to a substrate, an associated enzyme and a product (all of which can be searched). The ‘Drug Targets’ page includes options that allow users to search by drug, type of interaction (by filtering for enzyme, blood protein carrier and membrane transporter interactions) and biological entity. Four additional browse options, ‘Pharmaco-genomics’, ‘Pharmaco-metabolomics’, ‘Pharmaco-transcriptomics’ and ‘Pharmaco-proteomics’ are available; each containing relevant omic data linked to drugs. All browse pages also contain options to filter by drug group (such as ‘approved’) or market availability across the US, Canada and the EU.
