At study completion, we had screened 4630 subjects of whom over 2706 were eligible based on the inclusion criteria. We enrolled 2343 cases (86.6% of the eligible cases), of whom 179 (7.6%) were determined not to have lung cancer after diagnosis review; an additional 63 subjects had an uncertain diagnosis or were determined not to fit the inclusion criteria. Thus, subjects with confirmed diagnosis and characteristics fitting the inclusion and exclusion criteria were 2101. Epidemiological data and DNA specimens were collected from 98.4% and 97.3% of cases, respectively (Table 1).
