We thus now report 520,000 SNP genome wide association in pools of DNAs prepared from nicotine dependent European-American smoking cessation trial participants and control individuals. We compare genotypes from the entire group of nicotine dependent research participants to genotypes from European-American research volunteers free from any substantial lifetime use of any addictive substance. We also compare groups that displayed successful abstinence vs those who failed to display abstinence (Fig 1.).
