Chunk #9 — Results — Local genetic effects on blood gene expression

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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.

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Ninety-two percent of lead cis-eQTL SNPs were located within 100kb of the gene (Figure 2d) and stronger cis-eQTLs typically had a smaller distance between SNP and gene (within 20kb for 84.1% of the top 20% strongest eQTLs).