a nearby kinase gene, the Ankyrin Repeat and Kinase Domain Containing 1 (ANKK1) gene, where it causes a Glutamate→Lysine substitution [58], [59]. The results of the amino acid substitution are not known, but could impact interactions of the ANKK1 protein with other proteins including the dopamine D2 receptor [59]. No other polymorphism has been revealed in linkage disequilibrium with TaqI A that could easily account for these associations [41], [58]–[60].
