paperKB
coga / coga-kb
Processing
Help
Sign in

Chunk #0 — Introduction

Source
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
Embedded
yes

Text

The accumulation of abnormal amounts of intra-abdominal fat (central adiposity) is associated with serious adverse metabolic and cardiovascular outcomes, including type 2 diabetes (T2D) and atherosclerotic heart disease [1]. Indeed, because the medical consequences of increasing fat mass are disproportionately attributable to the extent of central adiposity, measures of overall adiposity, such as body mass index (BMI), fail to capture all of this risk [2],[3].