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Chunk #12 — MATERIALS AND METHODS — Genotyping

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Association of OPRD1 polymorphisms with heroin dependence in a large case-control series.
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Genotyping was performed on an Illumina BeadStation using the GoldenGate technology (Peters et al. 2008). DNA samples from CEPH trio 1334 (obtained from the Coriell Cell Repository) served as internal controls for quality of clustering and reproducibility. The primary analysis of the genotyping data with the Illumina BeadStudio software was followed by visual inspection and assessment of data quality and clustering.