measures of the response, together with a number of different genetic factors known to affect neurophysiological and neuroanatomical features. Since measures of the P3 response have been found to be useful endophenotypes for the study of substance abuse disorders (Euser et al., 2012; Iacono and Malone, 2011; Rangaswamy and Porjesz, 2008), externalizing psychopathology (Gilmore et al., 2012), schizophrenia (Decoster et al., 2012; Johannesen et al., 2013), and ADHD (Szuromi et al., 2011), and is highly heritable (van Beijsterveldt and van Baal, 2002), studies of genetic effects on P3 development in adolescents and young adults may illuminate neurophysiological and neuroanatomical factors contributing to the onset of these conditions.
