paperKB
coga / coga-kb
Help
Sign in

Chunk #16 — Methods — Measures — Ancestry informative genetic markers

Source
Prevention of Early Substance Use Mediates, and Variation at SLC6A4 Moderates, SAAF Intervention Effects on OXTR Methylation.
Embedded
yes

Text

Because population genetic admixture may confound G×E findings (Halder et al., 2009), we used the Structure program, version 2.3.4 (Falush, Stephens, & Pritchard, 2007) with a panel of 24 ancestry informative markers to estimate an ancestry proportion for each participant. Three ancestral populations (African, European, and Other) were found to be relevant to characterizing ancestry, and so racial admixture variables (Ancestry proportion 1, Ancestry proportion 2) were used as covariates in the analyses. Average level of European Ancestry was 28.9%