These findings are broadly consistent with earlier studies documenting the role of the dorsomedial and superior frontal cortices in inhibitory control and compromised activations of these structures in alcohol misuse (Abernathy et al., 2010). For instance, the ACC showed greater BOLD activities in light drinkers than in heavy drinkers for correct rejections in a go/no-go task (Ahmadi et al., 2013). In another study, activity of the ACC negatively correlated with the severity of alcohol misuse during correct rejections in the go/no-go task (Claus et al., 2013). In a spatial working memory task, Vollstadt-Klein et al. (2010) reported a trend of greater ACC activity in light than in heavy social drinkers. Adolescents with a family history of alcohol use disorder also showed less activation in the ACC and medial PFC than control adolescents during a spatial working memory (Spadoni et al., 2008) and emotional Stroop task (Qiao et al., 2015). The right dorsal prefrontal cortex demonstrated less BOLD activity in adolescents with a family history of alcoholism than those without during risky versus safe selection in a Wheel of Fortune task
