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Chunk #11 — Materials and methods — Genotyping and imputation

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Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.
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Genotype imputation was based on the 1000 Genomes phase 1 reference panel.34 Allelic dosage data were used to account for genotype uncertainties. See Supplementary Table 2 for the genotyping platform, imputation program and quality control thresholds used.