Descriptive statistics for age and BMI are presented by race and sex in Table 1. The mean age of participants was 48.8 and ranged from 18 to 90 and as depicted in Supplemental Fig. 1 produced a relatively normal distribution. BMI was not significantly associated with age (p = 0.135; Supplemental Fig. 2). Males were significantly older than females and European-American females and males were significantly older than African-American females and males (p < 0.0001). When partitioning the sample by clinically established BMI (kg/m2) categories, 29.0% was either under or normal weight (BMI<25), 33.4% was overweight (25 ≤ BMI < 30), 20.4% was obese class 1 (30≤ B BMI < 35), 9.5% was obese class II (35 ≤ BMI < 40) and7.7% was obese class III (40 ≤ BMI). There was a significant ancestry by sex interaction with BMI. As expected, females had significantly greater BMI than males with African-American females having greater BMI than European-American females and African-American males having greater BMI than European-American males (p <0.0001). Phenotypic findings in the MGS-C sample are consistent with cross-sectional data from
