The results are shown as mean±SEM. All statistical analysis was performed in SigmaStat 2.03 (SysStat Software, Point Richmont, CA). Differences between multiple groups were determined by 2-way ANOVA. Kaplan Meier plots were compared by log-rank test. For comparison between 2 independent groups the Students T-test were used. Significance was as accepted at p < 0.05.
