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Chunk #7 — Introduction — Alzheimer’s disease

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Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.
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Alzheimer’s disease is a progressive and irreversible neurodegenerative disorder that represents the most common cause of dementia in older populations (Alzheimer’s-Association, 2016) and is the sixth leading cause of death, accounting for 93,541 fatalities in 2014—a 54% increase since 1999 (Taylor, Greenlund, McGuire, Lu, & Croft, 2017). The National Institute on Aging (NIA) estimates that over 5 million Americans have Alzheimer’s disease, but this number may triple by 2050.