Model development is summarized in Table 1. The main analyses incorporated data on state suicides and medical marijuana policy through 2010. Model 1 of the main analyses included state and year indicators, state time-trends, and the six state covariates that were included in the comparison analyses. Model 2 included individual-level demographic covariates. The full model (Model 3) included the additional state covariates and a refined model (Model 4) removed covariates that were not significantly associated with suicide risk. Several post-hoc analyses were conducted to examine the association of these additional variables with state medical marijuana policy. These are described and summarized in the Supplemental Material.